Shane Jacobson has been appointed as the new CEO of the American Cancer Society (ACS) and the American Cancer Society Cancer Action Network (ACS CAN), sparking hopes for a transformative era in the fight against cancer.
At a Glance
- Shane Jacobson named CEO of ACS and ACS CAN, effective August 12, 2025.
- Jacobson has a proven track record in nonprofit management and fundraising.
- The leadership transition is expected to enhance cancer research funding and advocacy.
- Jacobson aims to increase stakeholder engagement and strategic planning efforts.
Strategic Leadership Transition
The American Cancer Society, a pillar in the fight against cancer since 1913, has announced a significant leadership change. Shane Jacobson, previously CEO of the V Foundation for Cancer Research, will take the helm as CEO of both ACS and its advocacy affiliate, ACS CAN. As of August 12, 2025, Jacobson will lead these organizations during a time when the stakes in cancer research and health policy have never been higher.
Thrilled to welcome Shane Jacobson as the new CEO of @AmericanCancer & ACS CAN! His leadership shows a deep commitment to & understanding of our mission to end cancer as we know it, for everyone. Looking forward to continuing our advocacy work together. https://t.co/dVN82jLg4P
— American Cancer Society Cancer Action Network (@ACSCAN) July 22, 2025
Jacobson is no stranger to the challenges of nonprofit leadership. At the V Foundation, he drove a 190% increase in revenue and a 275% rise in grantmaking over five years. This impressive track record has set high expectations for his new role, where he is tasked with aligning purpose with performance to maximize impact in cancer research and advocacy.
Expectations and Priorities
Jacobson’s appointment comes as ACS and ACS CAN are poised at a strategic inflection point. With Dr. Wayne A. I. Frederick having served as interim CEO since November 2024, the organizations are ready for a fresh strategic vision. Jacobson’s leadership is expected to boost fundraising initiatives, enhance stakeholder engagement, and refine long-term strategic plans.
Terri McClements, Chair of the ACS Board of Directors, expressed confidence in Jacobson’s ability to drive measurable outcomes. The ACS CAN President, Lisa A. Lacasse, echoed these sentiments, highlighting Jacobson’s strategic vision and dedication to the mission of ending cancer.
Impacts on Cancer Research and Advocacy
The appointment of Jacobson is anticipated to accelerate progress in cancer research funding and advocacy. The organizations aim to leverage Jacobson’s expertise to influence public policy more effectively and secure essential research funding. This could lead to increased support for cancer patients and families, as well as expanded research opportunities for healthcare providers.
Jacobson’s leadership is also expected to address health equity challenges, ensuring broader access to cancer prevention, detection, and treatment services across diverse communities. By strengthening advocacy efforts, ACS CAN hopes to achieve significant advancements in health policy, furthering the fight against cancer on multiple fronts.















